Yes, AutoCAD 2022 and AutoCAD LT 2022 are supported on Mac with Apple silicon models with an M series chip under Rosetta 2 mode.

AutoCAD 2022 and AutoCAD 2022 System Requirements

Rosetta 2 mode details: https://support.apple.com/en-us/HT211861

”Rosetta 2 works in the background whenever you use an app built only for Mac computers with an Intel processor. It automatically translates the app for use with Apple silicon. In most cases, you won't notice any difference in the performance of an app that needs Rosetta.”